Novel 5-azaindole factor VIIa inhibitors

Bioorg Med Chem Lett. 2006 Jun 15;16(12):3197-200. doi: 10.1016/j.bmcl.2006.03.049. Epub 2006 Apr 18.

Abstract

The discovery and development of 5-azaindole factor VIIa inhibitors will be described.

MeSH terms

  • Aza Compounds / chemical synthesis*
  • Aza Compounds / chemistry
  • Aza Compounds / pharmacology*
  • Crystallography, X-Ray
  • Factor VIIa / antagonists & inhibitors*
  • Factor VIIa / chemistry
  • Factor VIIa / metabolism
  • Indoles / chemical synthesis*
  • Indoles / chemistry
  • Indoles / pharmacology*
  • Models, Molecular
  • Molecular Structure
  • Structure-Activity Relationship

Substances

  • 5-azaindole
  • Aza Compounds
  • Indoles
  • Factor VIIa

Associated data

  • PDB/2FLR